The following Directorates and Corporations are functioning under the control of Health and Family Welfare Department

National Rural Health Mission Tamil Nadu 

TamilNadu Health System Project(TNHSP) 

Directorate of Medical Education

Directorate of Medical and Rural Health Services

Directorate of Public Health and Preventive Medicine

Directorate of Indian Medicine and Homeopathy

Directorate of Family Welfare

Directorate of Drugs Control 

Tamil Nadu Medical Services Corporation

Tamil Nadu State Health Transport Department

Tamil Nadu State AIDS Control Society 

Tamil Nadu State Blindness Control Society

DANIDA Health Care Project

Department of Food Safety & Drug Administration (Food Safety Division)

Medical Services Recruitment Board (MRB) 

Tamil Nadu Network for Organ Sharing

Transplant Authority of Tamil Nadu